发明申请
- 专利标题: New compounds for inhibiting differentiation of osteoclast and pharmaceutical composition comprising thereof
- 专利标题(中): 用于抑制破骨细胞分化的新化合物及其组合物
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申请号: US13664173申请日: 2012-10-30
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公开(公告)号: US20140031563A1公开(公告)日: 2014-01-30
- 发明人: Bae Keun Park , Sung-Hwa Yoon , Ju-Young Park , Sung Hoon Park
- 申请人: METACINE, INC.
- 申请人地址: KR Wonju
- 专利权人: Metacine, Inc.
- 当前专利权人: Metacine, Inc.
- 当前专利权人地址: KR Wonju
- 优先权: KR10-2012-0082248 20120727
- 主分类号: C07D207/452
- IPC分类号: C07D207/452 ; C07D207/20 ; C07D207/38
摘要:
New compounds and pharmaceutical compositions comprising active ingredients having inhibition effects on osteoclast differentiation are provided. The pharmaceutical compositions comprising the new compounds can be used as medicines for treating metabolic bone diseases such as bone metastatic cancer, solid cancer bone metastasis, musculoskeletal complication by solid cancer bone metastasis, hypercalcemia by malignant tumor, multiple myeloma, primary bone tumor, osteoporosis, rheumatoid arthritis, osteoarthritis, periodontal disease, inflammatory resorption of alveolar bone, inflammatory resorption of bone, and Paget's disease.
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