发明申请
US20140044644A1 ANKYRIN G AND MODULATORS THEREOF FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS
审中-公开
ANKYRIN G及其治疗神经损伤性疾病的调节剂
- 专利标题： ANKYRIN G AND MODULATORS THEREOF FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS
- 专利标题（中）： ANKYRIN G及其治疗神经损伤性疾病的调节剂
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申请号： US14000454申请日： 2012-02-21
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公开(公告)号： US20140044644A1公开(公告)日： 2014-02-13
- 发明人: Antonella Santuccione Chadha , Mario Merlini , Roger Nitsch , Jan Grimm , Christoph Hock
- 申请人： Antonella Santuccione Chadha , Mario Merlini , Roger Nitsch , Jan Grimm , Christoph Hock
- 申请人地址： CH Zurich
- 专利权人： UNIVERSITY OF ZURICH
- 当前专利权人： UNIVERSITY OF ZURICH
- 当前专利权人地址： CH Zurich
- 优先权： EP11001406.5 20110221
- 国际申请： PCT/EP12/52907 WO 20120221
- 主分类号： A61K39/395
- IPC分类号： A61K39/395 ; G01N33/68 ; A61K31/7088 ; A61K49/00 ; A61K38/17 ; A61K31/713
摘要：
The present invention generally relates to the technical field of medicine, in particular to the field of neurodegenerative, neurological and protein misfolding disorders such as amyloidosis. By establishing a role of ankG in APP processing the method of the present invention provides a new insight into the role of ankG in AD pathology and provides ankG as a target, drug, diagnostic agent and particularly as a vaccine in the treatment and diagnosis of the pathogenesis of Alzheimer's disease (AD).
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