发明申请
- 专利标题: BULK FREEZING OF BIOPHARMACEUTICALS
- 专利标题(中): 生物吸收的大容量冷冻
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申请号: US14008455申请日: 2012-03-27
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公开(公告)号: US20140047851A1公开(公告)日: 2014-02-20
- 发明人: Ying Zhou , Alan Cheng , Nigel Grinter , Zachary Fowler , Robert Sever , Ranko Bursac
- 申请人: Ying Zhou , Alan Cheng , Nigel Grinter , Zachary Fowler , Robert Sever , Ranko Bursac
- 申请人地址: US CT Danbury
- 专利权人: PRAXAIR TECHNOLOGY, INC.
- 当前专利权人: PRAXAIR TECHNOLOGY, INC.
- 当前专利权人地址: US CT Danbury
- 国际申请: PCT/US2012/030738 WO 20120327
- 主分类号: F25D3/10
- IPC分类号: F25D3/10
摘要:
A system and method for bulk freezing is provided. In one embodiment, the system and method for bulk freezing includes a bulk freezing container adapted to hold at least one and preferably a plurality of bags holding a biopharmaceutical liquid. The bulk freezing container includes at least a first and second shelf having corrugations wherein the second shelf is vertically arranged above the first shelf with the bags disposed between the shelves. The bags and the corrugations of the first and second shelves define a plurality of substantially parallel flow channels through which a cryogenic cold fluid or a warming fluid is passed to freeze and/or thaw the biopharmaceutical fluid. In another embodiment, the bulk freezing system and method includes a bulk freezing container with a plurality of adjacent elongated chambers adapted for holding the biopharmaceutical fluid. The adjacent elongated chambers have side walls defining a plurality of substantially parallel flow channels between the plurality of adjacent elongated chambers through which a heat transfer medium is passed for heat exchange through the side walls of the elongated chambers to the fluid within the elongated chambers.
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