A smart user-centric information aggregation system allows a user to define a region of content displayed in a display of a device and performs information aggregation on behalf of the user. The smart user-centric information aggregation system searches, aggregates and groups information related to content included in the region of content for the user while the user can continue to perform his/her original course of actions without interruption. After finding information related to the desired content, the smart user-centric information aggregation system may notify the user and present the found information to the user upon receiving confirmation from the user. The smart user-centric information aggregation system may continue to find new related information and update the presentation with the newly found information periodically, in some instances without user intervention or input.