Invention Application
US20140058056A1 MICROORGANISMS AND METHODS FOR ENHANCING THE AVAILABILITY OF REDUCING EQUIVALENTS IN THE PRESENCE OF METHANOL, AND FOR PRODUCING 1,4-BUTANEDIOL RELATED THERETO
有权
用于提高甲醇存在下降低等效物质和生产1,4-丁二醇相关物质的可行性的微生物和方法
- Patent Title: MICROORGANISMS AND METHODS FOR ENHANCING THE AVAILABILITY OF REDUCING EQUIVALENTS IN THE PRESENCE OF METHANOL, AND FOR PRODUCING 1,4-BUTANEDIOL RELATED THERETO
- Patent Title (中): 用于提高甲醇存在下降低等效物质和生产1,4-丁二醇相关物质的可行性的微生物和方法
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Application No.: US13975678Application Date: 2013-08-26
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Publication No.: US20140058056A1Publication Date: 2014-02-27
- Inventor: Anthony P. Burgard , Robin E. Osterhout , Stephen J. Van Dien , Cara Ann Tracewell , Priti Pharkya , Stefan Andrae
- Applicant: Genomatica, Inc.
- Applicant Address: US CA San Diego
- Assignee: Genomatica, Inc.
- Current Assignee: Genomatica, Inc.
- Current Assignee Address: US CA San Diego
- Main IPC: C12P7/18
- IPC: C12P7/18
Abstract:
Provided herein is a non-naturally occurring microbial organism having a methanol metabolic pathway that can enhance the availability of reducing equivalents in the presence of methanol. Such reducing equivalents can be used to increase the product yield of organic compounds produced by the microbial organism, such as 1,4-butanediol (BDO). Also provided herein are methods for using such an organism to produce BDO.
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