Cable structures for use in cable assemblies that interconnect portable electronic devices with various other devices, such as power adaptors, computers, media playback devices, etc. are shown. The cable structures can include a ground conductor that is broken up into multiple, smaller ground conductors that are physically separate and distinct from each other with the cable structure (and which can be terminated together in, for example, the connectors at the ends of the cable assembly). The cable structure may also include conductors having insulating material formed from FEP and/or wire mesh shield elements configured for high durability during bending and twisting of the assembled cable. An extrusion process can be used to manufacture the final, fully-assembled cable structure.