发明申请
- 专利标题： MUCIN ANTIGEN VACCINE
- 专利标题（中）： MUCIN ANGGEN VACCINE
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申请号： US13948573申请日： 2013-07-23
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公开(公告)号： US20140073045A1公开(公告)日： 2014-03-13
- 发明人: Yucheng Tang , Albert Deisseroth
- 申请人： MicroVAX, LLC
- 申请人地址： US VA Manassas
- 专利权人： MicroVAX, LLC.
- 当前专利权人： MicroVAX, LLC.
- 当前专利权人地址： US VA Manassas
- 主分类号： C12N15/85
- IPC分类号： C12N15/85
摘要：
Provided are expression vectors for generating an immune response to a mucin. The vectors comprise a transcription unit encoding a secretable polypeptide, the polypeptide comprising a secretory signal, a mucin antigen and CD40 ligand. Also provided are methods of generating an immune response against cells expressing a mucin by administering an effective amount of the vector. Further provided are methods of generating an immune response against cancer cells expressing a mucin in an individual by administering an effective amount of the vector. Still further provided are methods of overcoming anergy to a mucin self antigen by administering an effective amount of the vector.
公开/授权文献
- US08742087B2 Mucin antigen vaccine 公开/授权日：2014-06-03
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