An article of footwear may have an upper and a sole structure secured to the upper. The upper includes an illuminable panel and a plurality of strands positioned to extend adjacent and parallel to the illuminable panel. The illuminable panel has a surface with a covered area and an exposed area. The covered area includes a substantially opaque covering, and the exposed area is at least partially visible from the exterior of the footwear. The strands are located to correspond with the exposed area of the illuminable panel. Light from the exposed area of the illuminable panel may enhance, highlight, or otherwise increase the visibility of the strands or areas of the upper that include the strands.