The present invention provides a liquid crystal display module package box, which includes a box body, a retention frame arranged in the box body, and a cushioning device arranged in the box body. The retention frame forms therein a plurality of receiving channels corresponding to liquid crystal display modules. The cushioning device includes a first cushioning unit arranged between the retention frame and the box body and a plurality of second cushioning units arranged between the liquid crystal display modules and between the liquid crystal display modules and the box body. The first cushioning unit is formed by connecting a plurality of first air columns. The second cushioning unit is formed by connecting a plurality of second air columns. The liquid crystal display module package box provides a fully covered protection to the liquid crystal display modules received in the box body.