发明申请
US20140080809A1 Novel Compounds as Diacylglycerol Acyltransferase Inhibitors
有权
新型化合物作为二酰基甘油酰基转移酶抑制剂
- 专利标题： Novel Compounds as Diacylglycerol Acyltransferase Inhibitors
- 专利标题（中）： 新型化合物作为二酰基甘油酰基转移酶抑制剂
-
申请号： US14118976申请日： 2012-05-18
-
公开(公告)号： US20140080809A1公开(公告)日： 2014-03-20
- 发明人: Donghui Qin , Mui Cheung , Hemant Joshi , Raghuram Tangirala , Sridhar Reddy Bethi
- 申请人： Donghui Qin , Mui Cheung , Hemant Joshi , Raghuram Tangirala , Sridhar Reddy Bethi
- 申请人地址： GB Brentford, Middlesex
- 专利权人： GlaxoSmithKline Intellectual Property (No.2) Limited
- 当前专利权人： GlaxoSmithKline Intellectual Property (No.2) Limited
- 当前专利权人地址： GB Brentford, Middlesex
- 优先权： IN1452/DEL/2011 20110520
- 国际申请： PCT/US2012/038523 WO 20120518
- 主分类号： C07D498/04
- IPC分类号： C07D498/04
摘要：
This invention relates to novel compounds which are inhibitors of acyl coenzymeA: diacylglycerol acyltransferase 1 (DGAT-1), to pharmaceutical compositions containing them, to processes for their preparation, and to their use in therapy for the prevention or treatment of diseases related to DGAT-1 dysfunction or where modulation of DGAT-1 activity may have therapeutic benefit including but not limited to obesity, obesity related disorders, hypertriglyceridemia, hyperlipoproteinemia, chylomicronemia, dyslipidemia, non-alcoholic steatohepatitis, diabetes, insulin resistance, metabolic syndrome, hepatitis C virus infection and acne or other skin disorders.
公开/授权文献
- US08859536B2 Compounds as diacylglycerol acyltransferase inhibitors 公开/授权日：2014-10-14
信息查询
