发明申请
US20140086903A1 CD37 IMMUNOTHERAPEUTIC AND COMBINATION WITH BIFUNCTIONAL CHEMOTHERAPEUTIC THEREOF
审中-公开
CD37免疫组织化学与双功能化学疗法
- 专利标题： CD37 IMMUNOTHERAPEUTIC AND COMBINATION WITH BIFUNCTIONAL CHEMOTHERAPEUTIC THEREOF
- 专利标题（中）： CD37免疫组织化学与双功能化学疗法
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申请号： US13844269申请日： 2013-03-15
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公开(公告)号： US20140086903A1公开(公告)日： 2014-03-27
- 发明人: Philip TAN , Charles G. Cerveny , Sandy A. Simon , Anne Nilsson , William Brady , Peter A. Thompson , Cecile Morales
- 申请人： Philip TAN , Charles G. Cerveny , Sandy A. Simon , Anne Nilsson , William Brady , Peter A. Thompson , Cecile Morales
- 主分类号： A61K39/395
- IPC分类号： A61K39/395 ; A61K31/4184 ; A61K38/16
摘要：
The present disclosure provides a humanized anti-CD37 small modular immunopharmaceutical (SMIP) molecule, as well as synergistic combination therapies of CD37-specific binding molecules (such as anti-CD37 SMIP proteins or antibodies) with bifunctional chemotherapeutics (such as bendamustine) that can be administered concurrently or sequentially, for use in treating or preventing B-cell related autoimmune, inflammatory, or hyperproliferative diseases.