- 专利标题: APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES
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申请号: US14038304申请日: 2013-09-26
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公开(公告)号: US20140094471A1公开(公告)日: 2014-04-03
- 发明人: Milan Bruncko , Hong Ding , George A. Doherty , Steven W. Elmore , Lisa A. Hasvold , Laura Hexamer , Aaron R. Kunzer , Xiaohong Song , Andrew J. Souers , Gerard M. Sullivan , Zhi-Fu Tao , Gary T. Wang , Le Wang , Xilu Wang , Michael D. Wendt , Robert A. Mantei , Todd M. Hansen
- 申请人: AbbVie Inc. , The Walter and Eliza Hall Institute of Medical Research , Genentech, Inc.
- 申请人地址: US IL North Chicago AU Parkville US CA South San Francisco
- 专利权人: AbbVie Inc.,The Walter and Eliza Hall Institute of Medical Research,Genentech, Inc.
- 当前专利权人: AbbVie Inc.,The Walter and Eliza Hall Institute of Medical Research,Genentech, Inc.
- 当前专利权人地址: US IL North Chicago AU Parkville US CA South San Francisco
- 主分类号: C07D471/04
- IPC分类号: C07D471/04 ; C07D403/12 ; C07D209/82
摘要:
Disclosed are compounds which inhibit the activity of anti-apoptotic Bcl-2 proteins, compositions containing the compounds and methods of treating diseases during which is expressed anti-apoptotic Bcl-2 protein.
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