发明申请
- 专利标题: Cyclic Peptides with an Anti-Neoplasic and Anti-Angiogenic Activity
- 专利标题(中): 具有抗肿瘤和抗血管生成活性的环肽
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申请号: US14005855申请日: 2012-03-21
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公开(公告)号: US20140112976A1公开(公告)日: 2014-04-24
- 发明人: María del Carmen Abrahantes Pérez , Glay Chinea Santiago , Eduardo Martínez Díaz , Hilda Elisa Garay Perez , Osvaldo Reyes Acosta , Ernesto Lopez Mola , Cruz Matilde Lopez Abad , Sonia Gonzalez Blanco
- 申请人: María del Carmen Abrahantes Pérez , Glay Chinea Santiago , Eduardo Martínez Díaz , Hilda Elisa Garay Perez , Osvaldo Reyes Acosta , Ernesto Lopez Mola , Cruz Matilde Lopez Abad , Sonia Gonzalez Blanco
- 申请人地址: CU La Habana
- 专利权人: CENTRO DE INGENIERIA GENETICA BIOTECNOLOGIA
- 当前专利权人: CENTRO DE INGENIERIA GENETICA BIOTECNOLOGIA
- 当前专利权人地址: CU La Habana
- 优先权: CU2011/0067 20110321
- 国际申请: PCT/CU2012/000002 WO 20120321
- 主分类号: A61K38/12
- IPC分类号: A61K38/12 ; A61K31/4025 ; A61K45/06 ; C07K7/64
摘要:
The present invention comprises cyclic peptides bearing antitumor and antiangiogenic properties, as well as their corresponding pharmaceutically-suitable salts and also pharmaceutical compositions containing it. These cyclic peptides are used to prepare medicines for human and/or veterinary therapeutics, and additionally in diagnosis. These compounds can be used to detect, monitor and/or control a range of cellular proliferation-related disorders, such as oncological diseases and undesired angiogenesis. Moreover, they can be included as part of controlled release systems, and used more precisely in the field of nanobiotechnology, either because of their self-assembly capacity or as part of other systems.
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