发明申请
US20140127329A1 USE OF NITRITES FOR THE TREATMENT OF CEREBRAL AMYLOID ANGIOPATHY, AGE ASSOCIATED DEMENTIA, AND COGNITIVE DECLINE
审中-公开
使用NITRITES治疗谷氨酸血症,年龄相关DEMENTIA和认知衰退
- 专利标题: USE OF NITRITES FOR THE TREATMENT OF CEREBRAL AMYLOID ANGIOPATHY, AGE ASSOCIATED DEMENTIA, AND COGNITIVE DECLINE
- 专利标题(中): 使用NITRITES治疗谷氨酸血症,年龄相关DEMENTIA和认知衰退
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申请号: US14008267申请日: 2012-03-30
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公开(公告)号: US20140127329A1公开(公告)日: 2014-05-08
- 发明人: Anthony Giordano , Frank Greenway , Jeffrey Keller , Christpher Kevil
- 申请人: Anthony Giordano , Frank Greenway , Jeffrey Keller , Christpher Kevil
- 申请人地址: US LA Baton Rouge US OH Cleveland
- 专利权人: Board of Supervisors of Louisiana State University and Agricultural and Mechanical College,Thera Vasc Inc.
- 当前专利权人: Board of Supervisors of Louisiana State University and Agricultural and Mechanical College,Thera Vasc Inc.
- 当前专利权人地址: US LA Baton Rouge US OH Cleveland
- 国际申请: PCT/US2012/031459 WO 20120330
- 主分类号: A61K33/00
- IPC分类号: A61K33/00 ; A61K45/06
摘要:
The present invention relates to the medical use of nitrites, such as inorganic nitrites, or any pharmaceutically acceptable salts, solvates, compositions, or prodrugs thereof, in the treatment of conditions that benefit from increased cerebral vascular flow. The pharmaceutical compositions used in these methods, which can be formulated for oral administration, can provide immediate release or extended release of the nitrite ion (NO2−).
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