发明申请
- 专利标题： ALKYNE SUBSTITUTED QUINAZOLINE COMPOUND AND METHODS OF USE
- 专利标题（中）： ALKYNE取代的喹唑啉化合物及其使用方法
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申请号： US14002983申请日： 2012-03-02
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公开(公告)号： US20140128417A1公开(公告)日： 2014-05-08
- 发明人: Wang Shen , Aimin Zhang , Jack Maung , Xiaoling Zheng
- 申请人： Wang Shen , Aimin Zhang , Jack Maung , Xiaoling Zheng
- 申请人地址： US CA Menlo Park
- 专利权人： Newgen Therapeutics, Inc.
- 当前专利权人： Newgen Therapeutics, Inc.
- 当前专利权人地址： US CA Menlo Park
- 国际申请： PCT/US12/27614 WO 20120302
- 主分类号： C07D405/06
- IPC分类号： C07D405/06
摘要：
The invention provides alkyne substituted quinazoline compounds, such as compounds of the formula (I), which are irreversible ErbB kinase inhibitors. The compounds are useful in the treatment of diseases and disorders where ErbB kinase activity is implicated such as a hyperproliferative disorder (e.g., cancer).
公开/授权文献
- US09090588B2 Alkyne substituted quinazoline compound and methods of use 公开/授权日：2015-07-28
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