Invention Application
- Patent Title: AKT PROTEIN KINASE INHIBITORS
- Patent Title (中): AKT蛋白激酶抑制剂
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Application No.: US14170272Application Date: 2014-01-31
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Publication No.: US20140148436A1Publication Date: 2014-05-29
- Inventor: Ian S. Mitchell , Keith L. Spencer , Peter Stengel , Yongxin Han , Nicolas C. Kallan , Mark Munson , Guy P.A. Vigers , James Blake , Anthony Piscopio , John Josey , Scott Miller , Dengming Xiao , Rui Xu , Chang Rao , Bing Wang , April L. Bernacki
- Applicant: Array BioPharma, Inc.
- Applicant Address: US CO Boulder
- Assignee: Array BioPharma, Inc.
- Current Assignee: Array BioPharma, Inc.
- Current Assignee Address: US CO Boulder
- Main IPC: C07D239/94
- IPC: C07D239/94 ; C07D403/12 ; C07D495/04 ; C07D491/048 ; C07D231/56 ; C07D401/12 ; C07D409/04 ; C07D401/04 ; C07D409/12 ; C07D487/04
Abstract:
The present invention provides compounds, including resolved enantiomers, diastereomers, solvates and pharmaceutically acceptable salts thereof, comprising the Formula: A-L-CR where CR is a cyclical core group, L is a linking group and A is as defined herein. Also provided are methods of using the compounds of this invention as AKT protein kinase inhibitors and for the treatment of hyperproliferative diseases such as cancer.
Public/Granted literature
- US20160152576A9 AKT PROTEIN KINASE INHIBITORS Public/Granted day:2016-06-02
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