A cutting insert, a cutting tool and method of manufacturing a machined product. The cutting insert includes: upper and lower surfaces; a side surface; a cutting edge; and a rake portion on the upper surface. The cutting edge includes major and minor cutting edges that are convex toward outside of the main body portion. The minor cutting edge has a curvature radius smaller than a curvature radius of the major cutting edge. The rake portion is inclined and approaches the lower surface as moving from the major cutting edge toward inside of the main body portion and is located along the major cutting edge. An inclination angle of the rake portion becomes smaller as moving from a part continuous with one end of the major cutting edge toward a part continuous with center of the major cutting edge.