Invention Application
- Patent Title: THERAPEUTIC AGENT FOR ECTOPIC PREGNANCY
- Patent Title (中): 用于经济性怀孕的治疗药物
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Application No.: US13977434Application Date: 2011-12-28
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Publication No.: US20140179677A1Publication Date: 2014-06-26
- Inventor: Kazuhiro Kawamura
- Applicant: Kazuhiro Kawamura
- Applicant Address: JP Akita-shi, Akita
- Assignee: AKITA UNIVERSITY
- Current Assignee: AKITA UNIVERSITY
- Current Assignee Address: JP Akita-shi, Akita
- Priority: JP2010-294391 20101229
- International Application: PCT/JP2011/080466 WO 20111228
- Main IPC: C07D498/22
- IPC: C07D498/22 ; G01N33/50

Abstract:
A novel therapeutic agent for ectopic pregnancy having a therapeutic effect for ectopic pregnancy, especially unruptured ectopic pregnancy, and a novel method of screening a therapeutic agent for ectopic pregnancy are disclosed. The therapeutic agent for ectopic pregnancy contains as an effective ingredient a suppressor of brain-derived neurotrophic factor (BDNF) and/or of brain-derived neurotrophic factor receptor (TrkB). The method of screening a therapeutic agent for ectopic pregnancy includes measuring the kinase activity of TrkB in the presence of a test substance and the kinase activity of TrkB in the absence of the test substance; and selecting the test substance which decreases the kinase activity of TrkB.
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