发明申请
US20140179780A1 PHARMACEUTICAL COMPOSITION CONTAINING OLEANOLIC ACID ACETATE AS AN ACTIVE INGREDIENT FOR PREVENTING OR TREATING TLR- OR IL-6-MEDIATED DISEASES
审中-公开
含有油酸乙酸酯作为预防或治疗TLR或IL-6介导性疾病的活性成分的药物组合物
- 专利标题： PHARMACEUTICAL COMPOSITION CONTAINING OLEANOLIC ACID ACETATE AS AN ACTIVE INGREDIENT FOR PREVENTING OR TREATING TLR- OR IL-6-MEDIATED DISEASES
- 专利标题（中）： 含有油酸乙酸酯作为预防或治疗TLR或IL-6介导性疾病的活性成分的药物组合物
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申请号： US14114559申请日： 2012-04-30
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公开(公告)号： US20140179780A1公开(公告)日： 2014-06-26
- 发明人: Mun Chual Rho , Woo Song Lee , Hyun Mee Oh , Young Min Kim , Young Bae Ryu , Su Jin Park , Seung Woong Lee , Kyoung Oh Cho
- 申请人： Mun Chual Rho , Woo Song Lee , Hyun Mee Oh , Young Min Kim , Young Bae Ryu , Su Jin Park , Seung Woong Lee , Kyoung Oh Cho
- 申请人地址： KR Daejeon
- 专利权人： Korea Research Institute of Bioscience and Biotechnology
- 当前专利权人： Korea Research Institute of Bioscience and Biotechnology
- 当前专利权人地址： KR Daejeon
- 优先权： KR10-2011-0041189 20110429; KR10-2011-0098547 20110928
- 国际申请： PCT/KR2012/003383 WO 20120430
- 主分类号： A61K31/19
- IPC分类号： A61K31/19 ; A61K36/48
摘要：
The present invention relates to a pharmaceutical composition including oleanolic acid acetate or a pharmaceutically acceptable salt thereof as an active ingredient for preventing or treating TLR- and IL-6-mediated diseases, and a pharmaceutical composition including an adzuki bean extract containing the compound or the salt thereof, or a fraction thereof as an active ingredient for preventing or treating TLR- and IL-6-mediated diseases. The adzuki bean extract or the compound of the present invention is derived from a natural resource that has been used as a natural medicine for a long time, and it is widely used for the development of prophylactic or therapeutic agents for TLR- and IL-6-mediated diseases, for example, atopic dermatitis or arthritis.