发明申请
- 专利标题: METHODS OF PRODUCING 6-CARBON CHEMICALS VIA CoA-DEPENDENT CARBON CHAIN ELONGATION ASSOCIATED WITH CARBON STORAGE
- 专利标题(中): 通过与碳储存相关的辅助碳链延伸生产6碳化合物的方法
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申请号: US14106124申请日: 2013-12-13
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公开(公告)号: US20140186902A1公开(公告)日: 2014-07-03
- 发明人: Adriana Leonora Botes , Alex Van Eck Conradie
- 申请人: INVISTA North America S. a r.l.
- 申请人地址: US DE Wilmington
- 专利权人: INVISTA North America S. a r.l.
- 当前专利权人: INVISTA North America S. a r.l.
- 当前专利权人地址: US DE Wilmington
- 主分类号: C12P13/00
- IPC分类号: C12P13/00 ; C12P7/18 ; C12P7/44
摘要:
This document describes biochemical pathways for producing adipic acid, caprolactam, 6-aminohexanoic acid, 6-hydroxyhexanoic acid, hexamethylenediamine or 1,6-hexanediol by forming two terminal functional groups, comprised of carboxyl, amine or hydroxyl groups, in a C6 aliphatic backbone substrate. These pathways, metabolic engineering and cultivation strategies described herein rely on CoA-dependent elongation enzymes or analogues enzymes associated with the carbon storage pathways from polyhydroxyalkanoate accumulating bacteria.