发明申请
- 专利标题: ANTI-GDF15 ANTIBODIES
- 专利标题(中): 抗GDF15抗体
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申请号: US14137415申请日: 2013-12-20
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公开(公告)号: US20140193427A1公开(公告)日: 2014-07-10
- 发明人: Lorena Lerner , Sandra Abbott , Ailin Bai , Ting Chen , Maria Isabel Chiu , Qing Liu , Laura Poling , Nianjun Tao , Solly Weiler , Zhigang Weng , William M. Winston, Jr. , Jeno Gyuris
- 申请人: AVEO Pharmaceuticals, Inc.
- 申请人地址: US MA Cambridge
- 专利权人: AVEO PHARMACEUTICALS, INC.
- 当前专利权人: AVEO PHARMACEUTICALS, INC.
- 当前专利权人地址: US MA Cambridge
- 主分类号: C07K16/22
- IPC分类号: C07K16/22
摘要:
Monoclonal antibodies that bind and inhibit the activity of human GDF15 are disclosed. The antibodies can be used to treat body weight loss, including cachexia, associated with the over-expression of human GDF15.
公开/授权文献
- US09175076B2 Anti-GDF15 antibodies 公开/授权日:2015-11-03
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