发明申请
US20140212481A1 IMMUNOLOGICAL METHODS AND COMPOSITIONS FOR THE TREATMENT OF ALZHEIMER'S DISEASE
审中-公开
用于治疗阿尔茨海默病的免疫学方法和组合物
- 专利标题： IMMUNOLOGICAL METHODS AND COMPOSITIONS FOR THE TREATMENT OF ALZHEIMER'S DISEASE
- 专利标题（中）： 用于治疗阿尔茨海默病的免疫学方法和组合物
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申请号： US14246830申请日： 2014-04-07
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公开(公告)号： US20140212481A1公开(公告)日： 2014-07-31
- 发明人: Peter H. St. George-Hyslop , JoAnne McLaurin
- 申请人： Peter H. St. George-Hyslop , JoAnne McLaurin
- 主分类号： C07K16/18
- IPC分类号： C07K16/18 ; G01N33/68 ; C07K14/47
摘要：
The present invention relates to immunogenic compositions and peptides comprising residues 4-10 (FRHDSGY) of the amyloid peptide Abeta42. The invention further relates to antibodies that bind to the Abeta(4-10) antigenic determinant. The invention provides methods for treating Alzheimer's disease and for reducing the amyloid load in Alzheimers patients. The invention also relates to methods for designing small molecule inhibitors of amyloid deposition.
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