发明申请
US20140221475A1 PLATINUM(IV) COMPLEXES AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME 审中-公开
铂(IV)复合物和含有它们的药物组合物

  • 专利标题: PLATINUM(IV) COMPLEXES AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME
  • 专利标题(中): 铂(IV)复合物和含有它们的药物组合物
  • 申请号: US14232719
    申请日: 2012-07-09
  • 公开(公告)号: US20140221475A1
    公开(公告)日: 2014-08-07
  • 发明人: Hisae AraiHisao KondoNorio Masuda
  • 申请人: Hisae AraiHisao KondoNorio Masuda
  • 申请人地址: JP Chiba
  • 专利权人: UNITECH CO., LTD.
  • 当前专利权人: UNITECH CO., LTD.
  • 当前专利权人地址: JP Chiba
  • 优先权: JP2011-156527 20110715
  • 国际申请: PCT/JP2012/067471 WO 20120709
  • 主分类号: C07F15/00
  • IPC分类号: C07F15/00
PLATINUM(IV) COMPLEXES AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME
摘要:
New platinum(IV) complexes which has a strong antitumor activity and has a feature that a side effect is relatively reduced is provided. The new complex is platinum(IV) complexes with cis,cis-spiro[4,4]nonane-1,6-diamine ligand and is platinum(IV) complexes with optically active cis,cis-spiro[4,4]nonane-1,6-diamine ligand. Especially, the new complex is dichloromalonato((1S,5S,6S)-spiro[4.4]nonane-1,6-diamine)platinum(IV).
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