发明申请
US20140228235A1 MICROARRAY DEVICE FOR SCREENING OR LOCATING HSP90 INHIBITORS OR INHIBITORS OF FURTHER DISEASE-RELEVANT TARGET STRUCTURES
有权
用于筛选或定位HSP90抑制剂或进一步疾病相关目标结构的抑制剂的微阵列装置
- 专利标题： MICROARRAY DEVICE FOR SCREENING OR LOCATING HSP90 INHIBITORS OR INHIBITORS OF FURTHER DISEASE-RELEVANT TARGET STRUCTURES
- 专利标题（中）： 用于筛选或定位HSP90抑制剂或进一步疾病相关目标结构的抑制剂的微阵列装置
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申请号： US14128298申请日： 2012-04-20
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公开(公告)号： US20140228235A1公开(公告)日： 2014-08-14
- 发明人: Dieter Melzner , Thomas Scheper , Thomas Schuler , Frank Stahl , Denise Van Rossum , Johanna-Gabriela Walter , Carsten Zeilinger
- 申请人： Dieter Melzner , Thomas Scheper , Thomas Schuler , Frank Stahl , Denise Van Rossum , Johanna-Gabriela Walter , Carsten Zeilinger
- 优先权： DE102011106984.8 20110708
- 国际申请： PCT/EP2012/001725 WO 20120420
- 主分类号： G01N33/68
- IPC分类号： G01N33/68
摘要：
The present invention relates to a microarray device for the screening or the finding of protein inhibitors, to a method for the production thereof, and to a corresponding method for screening or finding protein inhibitors. The microarray device according to the invention comprises a solid supporting element having a support material, at least one protein immobilized thereon for which inhibitors are to be screened or found, and at least one known inhibitor of the at least one protein, the inhibitor being bound to the at least one protein and comprising a detectable label.