发明申请
- 专利标题: Multi-Substituted Insulins
- 专利标题(中): 多取代胰岛素
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申请号: US14126215申请日: 2012-06-14
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公开(公告)号: US20140228285A1公开(公告)日: 2014-08-14
- 发明人: Thomas Hoeg-Jensen , Peter Madsen , Jane Spetzler , Tina Moeller Tagmose
- 申请人: Thomas Hoeg-Jensen , Peter Madsen , Jane Spetzler , Tina Moeller Tagmose
- 申请人地址: DK Bagsvaerd
- 专利权人: NOVO NORDISK A/S
- 当前专利权人: NOVO NORDISK A/S
- 当前专利权人地址: DK Bagsvaerd
- 优先权: EP11170009.2 20110615
- 国际申请: PCT/EP2012/061284 WO 20120614
- 主分类号: C07K14/62
- IPC分类号: C07K14/62
摘要:
The present invention regards an insulin derivative comprising at least 2 albumin binding moieties, wherein said albumin binding moieties comprise fatty diacid substitutions and a method for preparing such an insulin derivative by acylation and/or reductive alkylation. The present invention also concern a pharmaceutical comprising such an insulin derivative.
公开/授权文献
- US09260503B2 Multi-substituted insulins 公开/授权日:2016-02-16
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