发明申请
- 专利标题： COMPOSITIONS OF PROTEIN RECEPTOR TYROSINE KINASE INHIBITORS
- 专利标题（中）： 蛋白质受体酪氨酸激酶抑制剂的组成
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申请号： US14256094申请日： 2014-04-18
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公开(公告)号： US20140228331A1公开(公告)日： 2014-08-14
- 发明人: Jay Jie-Qiang Wu , Ling Wang
- 申请人： VM Pharma LLC
- 主分类号： C07D261/20
- IPC分类号： C07D261/20 ; A61K31/496 ; A61K45/06
摘要：
The present invention relates to novel synthetic substituted heterocyclic compounds and pharmaceutical compositions containing the same that are capable of inhibiting or antagonizing a family of receptor tyrosine kinases, Tropomysosin Related Kinases (Trk), in particular the nerve growth factor (NGF) receptor, TrkA. The invention further concerns the use of such compounds in the treatment and/or prevention of pain, cancer, restenosis, atherosclerosis, psoriasis, thrombosis, or a disease, disorder or injury relating to dysmyelination or demyelination or the disease or disorder associated with abnormal activities of NGF receptor TrkA.
公开/授权文献
- US08809530B1 Compositions of protein receptor tyrosine kinase inhibitors 公开/授权日：2014-08-19
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