发明申请
- 专利标题： NOVEL ROCK KINASE INHIBITORS
- 专利标题（中）： 新型摇滚激酶抑制剂
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申请号： US14241092申请日： 2012-08-31
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公开(公告)号： US20140228408A1公开(公告)日： 2014-08-14
- 发明人: Jo Alen , Sandro Boland , Arnaud Pierre, Jean Bourin , Olivier Defert , Dirk Leysen
- 申请人： Jo Alen , Sandro Boland , Arnaud Pierre, Jean Bourin , Olivier Defert , Dirk Leysen
- 申请人地址： BE Diepenbeek
- 专利权人： AMAKEM NV
- 当前专利权人： AMAKEM NV
- 当前专利权人地址： BE Diepenbeek
- 优先权： EP11179491.3 20110831
- 国际申请： PCT/EP2012/067016 WO 20120831
- 主分类号： C07D213/75
- IPC分类号： C07D213/75 ; C07D405/12 ; C07D401/12
摘要：
The present invention relates to new kinase inhibitors, more specifically ROCK inhibitors, compositions, in particular pharmaceuticals, comprising such inhibitors, and to uses of such inhibitors in the treatment and prophylaxis of disease. In particular, the present invention relates to new ROCK inhibitors, compositions, in particular pharmaceuticals, comprising such inhibitors, and to uses of such inhibitors in the treatment and prophylaxis of disease. In addition, the invention relates to methods of treatment and use of said compounds in the manufacture of a medicament for the application to a number of therapeutic indications including sexual dysfunction, inflammatory diseases, ophthalmic diseases and respiratory diseases.
公开/授权文献
- US09079858B2 Rock kinase inhibitors 公开/授权日：2015-07-14
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