发明申请
US20140234372A1 NOVEL VLPS DERIVED FROM CELLS THAT DO NOT EXPRESS A VIRAL MATRIX OR CORE PROTEIN
有权
从不能表达病毒基质或核心蛋白质的细胞衍生的新型VLPS
- 专利标题： NOVEL VLPS DERIVED FROM CELLS THAT DO NOT EXPRESS A VIRAL MATRIX OR CORE PROTEIN
- 专利标题（中）： 从不能表达病毒基质或核心蛋白质的细胞衍生的新型VLPS
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申请号： US14252043申请日： 2014-04-14
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公开(公告)号： US20140234372A1公开(公告)日： 2014-08-21
- 发明人: Gale SMITH , Peter Pushko , Kutub Mahmood , Bin Zhou
- 申请人： NOVAVAX, INC.
- 主分类号： A61K39/145
- IPC分类号： A61K39/145
摘要：
The present invention discloses novel influenza virus-like particles (VLPs) that contain chimeric proteins or influenza membrane proteins. The chimeric proteins are derived from fragments of influenza membrane proteins fused to heterologous proteins. The invention includes antigenic formulations and vaccines comprising VLPs of the invention as well as methods of making and administering VLPs to vertebrates, including methods of inducing immunity to infections, such as influenza.
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