发明申请
US20140242575A1 KITS AND METHODS FOR IN VITRO ANALYTE DETECTION USING PRECIPITATING COMPOUND AND POLARIZERS
审中-公开
使用预处理化合物和极化剂进行体内分析检测的试剂盒和方法
- 专利标题： KITS AND METHODS FOR IN VITRO ANALYTE DETECTION USING PRECIPITATING COMPOUND AND POLARIZERS
- 专利标题（中）： 使用预处理化合物和极化剂进行体内分析检测的试剂盒和方法
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申请号： US14190367申请日： 2014-02-26
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公开(公告)号： US20140242575A1公开(公告)日： 2014-08-28
- 发明人: Gary Opperman
- 申请人： SurModics, Inc.
- 主分类号： G01N33/543
- IPC分类号： G01N33/543
摘要：
The invention provides inexpensive kits and methods for determination of an analyte in a sample with very high sensitivity. Analyte can be determined using an analyte binding member such as an antibody or an oligonucleotide, which can be directly or indirectly linked to an enzyme. The kit and method uses a compound that is altered in the presence of the enzyme, and that precipitates into crystalline particulates. The reaction composition with crystalline particulates is placed between two polarizers which are in an orthogonal arrangement, and the presence of particulates is observed, correlating to the analyte in the sample.
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