发明申请
- 专利标题: NOVEL COMPOUND HAVING PARP INHIBITORY ACTIVITY
- 专利标题(中): 具有PARP抑制活性的新型化合物
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申请号: US14232160申请日: 2012-07-12
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公开(公告)号: US20140243320A1公开(公告)日: 2014-08-28
- 发明人: Takahiro Honda , Hiroshi Enomoto , Kenji Kawashima , Shinji Takaoka , Yasutaka Fujioka , Mamoru Matsuda , Koji Ohashi , Yukie Fujita , Shin-ichiro Hirai , Hiroaki Kurashima
- 申请人: Takahiro Honda , Hiroshi Enomoto , Kenji Kawashima , Shinji Takaoka , Yasutaka Fujioka , Mamoru Matsuda , Koji Ohashi , Yukie Fujita , Shin-ichiro Hirai , Hiroaki Kurashima
- 申请人地址: JP Osaka-shi
- 专利权人: SANTEN PHARMACEUTICAL CO., LTD.
- 当前专利权人: SANTEN PHARMACEUTICAL CO., LTD.
- 当前专利权人地址: JP Osaka-shi
- 优先权: JP2011-154636 20110713
- 国际申请: PCT/JP2012/067775 WO 20120712
- 主分类号: C07D487/06
- IPC分类号: C07D487/06 ; C07D519/00 ; C07D495/14
摘要:
A compound represented by the following general formula (1) or a salt thereof. R1 represents a halogen atom and so on; R2 and R3 each represent a hydrogen atom and so on; R4 and R5 each represent a hydrogen atom and so on, or R4 and R5 may form an oxo group; Ra and Rb each represent a lower alkyl group optionally having a substituent and so on, or they may bind to each other to form a nitrogen-containing heterocyclic ring which may be substituted by one or plural Rc; Rc represents an aryl group optionally having a substituent and so on; ring A represents a benzene ring and so on; and m represents 0, 1 or 2.
公开/授权文献
- US09062061B2 Compound having PARP inhibitory activity 公开/授权日:2015-06-23
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