Invention Application
US20140243338A1 PHENYLPYRAZOLE DERIVATIVES AS POTENT ROCK1 AND ROCK2 INHIBITORS
有权
作为POTENT ROCK1和ROCK2抑制剂的苯基吡唑衍生物
- Patent Title: PHENYLPYRAZOLE DERIVATIVES AS POTENT ROCK1 AND ROCK2 INHIBITORS
- Patent Title (中): 作为POTENT ROCK1和ROCK2抑制剂的苯基吡唑衍生物
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Application No.: US14192955Application Date: 2014-02-28
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Publication No.: US20140243338A1Publication Date: 2014-08-28
- Inventor: Mimi L. Quan , Zilun Hu , Cailan Wang
- Applicant: Bristol-Myers Squibb Company
- Main IPC: C07D231/12
- IPC: C07D231/12 ; C07D401/12 ; C07D417/12
Abstract:
The present invention provides compounds of Formula (I): or stereoisomers, tautomers, or pharmaceutically acceptable salts thereof, wherein all the variables are as defined herein. These compounds are selective ROCK inhibitors. This invention also relates to pharmaceutical compositions comprising these compounds and methods of treating cardiovascular, smooth muscle, oncologic, neuropathologic, autoimmune, fibrotic, and/or inflammatory disorders using the same.
Public/Granted literature
- US09126944B2 Phenylpyrazole derivatives as potent ROCK1 and ROCK2 inhibitors Public/Granted day:2015-09-08
Information query
