发明申请
- 专利标题： TREATMENT OF COAGULOPATHY WITH HYPERFIBRINOLYSIS
- 专利标题（中）： 用高效液相色谱处理凝血病
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申请号： US14026037申请日： 2013-09-13
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公开(公告)号： US20140256640A1公开(公告)日： 2014-09-11
- 发明人: Karl-Uwe Petersen , Michael Ernest Nesheim , Jonathan Herbert Foley
- 申请人： Karl-Uwe Petersen , Michael Ernest Nesheim , Jonathan Herbert Foley
- 申请人地址： DE Aachen
- 专利权人： Paion Deutschland GmbH
- 当前专利权人： Paion Deutschland GmbH
- 当前专利权人地址： DE Aachen
- 主分类号： C07K14/745
- IPC分类号： C07K14/745 ; C12Q1/56
摘要：
The present invention relates to the use of thrombomodulin analogues for the manufacture of a medicament for the treatment of coagulopathy with hyperfibrinolysis, such as haemophilia disorders. These thrombomodulin analogs exhibit at therapeutically effective dosages an antifibrinolytic effect. Novel protein modifications together with methods for their identification are disclosed.
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