发明申请
US20140256704A1 Substituted 1H-Pyrrolo [2, 3-b] pyridine and 1H-Pyrazolo [3, 4-b] pyridine Derivatives as Salt Inducible Kinase 2 (SIK2) Inhibitors
有权
取代的1H-吡咯并[2,3-b]吡啶和1H-吡唑并[3,4-b]吡啶衍生物作为盐诱导型激酶2（SIK2）抑制剂
![Substituted 1H-Pyrrolo [2, 3-b] pyridine and 1H-Pyrazolo [3, 4-b] pyridine Derivatives as Salt Inducible Kinase 2 (SIK2) Inhibitors](/docs/US/2014-09-11/US20140256704A1/abs.jpg.600x600.jpg)
- 专利标题： Substituted 1H-Pyrrolo [2, 3-b] pyridine and 1H-Pyrazolo [3, 4-b] pyridine Derivatives as Salt Inducible Kinase 2 (SIK2) Inhibitors
- 专利标题（中）： 取代的1H-吡咯并[2,3-b]吡啶和1H-吡唑并[3,4-b]吡啶衍生物作为盐诱导型激酶2（SIK2）抑制剂
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申请号： US14101109申请日： 2013-12-09
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公开(公告)号： US20140256704A1公开(公告)日： 2014-09-11
- 发明人: Hariprasad Vankayalapati , Venkatakrishnareddy Yerramreddy , Venu Babu Ganipisetty , Sureshkumar Talluri , Rajendra P. Appalaneni
- 申请人： Arrien Pharmaceuticals LLC
- 申请人地址： US NJ Somerset
- 专利权人： ARRIEN PHARMACEUTICALS LLC
- 当前专利权人： ARRIEN PHARMACEUTICALS LLC
- 当前专利权人地址： US NJ Somerset
- 主分类号： C07D471/04
- IPC分类号： C07D471/04
![Substituted 1H-Pyrrolo [2, 3-b] pyridine and 1H-Pyrazolo [3, 4-b] pyridine Derivatives as Salt Inducible Kinase 2 (SIK2) Inhibitors](/abs-image/US/2014/09/11/US20140256704A1/abs.jpg.150x150.jpg)
摘要：
The present invention relates to compounds according to Formulas I, IA or IB: to pharmaceutically acceptable composition, salts thereof, their synthesis and their use as SIK2 inhibitors including such compounds and methods of using said compounds in the treatment of various diseases and or disorders such as cancer, stroke, cardiovascular, obesity and type II diabetes.