发明申请
US20140271484A1 Methods of Imaging Inflammatory Diseases by Ligands Conjugated to Fluorescent Compounds
有权
通过与荧光化合物共轭的配体成像炎症疾病的方法
- 专利标题： Methods of Imaging Inflammatory Diseases by Ligands Conjugated to Fluorescent Compounds
- 专利标题（中）： 通过与荧光化合物共轭的配体成像炎症疾病的方法
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申请号： US14135099申请日： 2013-12-19
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公开(公告)号： US20140271484A1公开(公告)日： 2014-09-18
- 发明人: Philip S. Low , Sumith A. Kularatne , Lindsay E. Kelderhouse
- 申请人： Purdue Research Foundation
- 申请人地址： US IN West Lafayette
- 专利权人： Purdue Research Foundation
- 当前专利权人： Purdue Research Foundation
- 当前专利权人地址： US IN West Lafayette
- 主分类号： A61K49/00
- IPC分类号： A61K49/00
摘要：
The present disclosure relates to compounds that are useful as near-infrared fluorescence probes, wherein the compounds include i) a pteroyl ligand that binds to a target receptor protein, ii) a dye molecule, and iii) a linker molecule that comprises an amino acid or derivative thereof. The disclosure further describes methods of imaging of inflammatory diseases using the compounds.
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