发明申请
- 专利标题： IN VIVO TEMPORAL CONTROL OF ACTIVATABLE MATRIX-DEGRADING ENZYMES
- 专利标题（中）： 可激活基质降解酶的体外时间控制
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申请号： US14243805申请日： 2014-04-02
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公开(公告)号： US20140271609A1公开(公告)日： 2014-09-18
- 发明人: Gilbert Keller , Gregory I. Frost
- 申请人： Gilbert Keller , Gregory I. Frost
- 主分类号： A61K38/48
- IPC分类号： A61K38/48
摘要：
Methods and combinations are provided for controlling the duration of action, in vivo, of matrix-degrading enzymes. The methods and combinations permit temporary in-vivo activation of matrix-degrading enzymes upon administration to the extra cellular matrix (or “ECM”). Matrix-degrading enzymes having a controlled duration of action can be used to treat ECM-mediated diseases or disorders characterized by increased deposition or accumulation of one or more ECM components.
公开/授权文献
- US09775889B2 Methods of treatment of cellulite 公开/授权日：2017-10-03
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