发明申请
US20140274936A1 COORDINATION COMPLEXES, PHARMACEUTICAL SOLUTIONS COMPRISING COORDINATION COMPLEXES, AND METHODS OF TREATING PATIENTS
审中-公开
协调复合物，包含协调复合物的药物溶液和治疗患者的方法
- 专利标题： COORDINATION COMPLEXES, PHARMACEUTICAL SOLUTIONS COMPRISING COORDINATION COMPLEXES, AND METHODS OF TREATING PATIENTS
- 专利标题（中）： 协调复合物，包含协调复合物的药物溶液和治疗患者的方法
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申请号： US14290877申请日： 2014-05-29
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公开(公告)号： US20140274936A1公开(公告)日： 2014-09-18
- 发明人: Thomas Piccariello , John D. Price , Robert A. Oberlender , Michaela E. Mulhare , Mary C. Spencer , Scott B. Palmer
- 申请人： SYNTHONICS, INC.
- 申请人地址： US VA BLACKSBURG
- 专利权人： SYNTHONICS, INC.
- 当前专利权人： SYNTHONICS, INC.
- 当前专利权人地址： US VA BLACKSBURG
- 主分类号： C07H17/02
- IPC分类号： C07H17/02 ; C07F3/02 ; C07F15/04 ; C07F3/00 ; C07F3/06 ; C07F15/02
摘要：
A coordination complex having a physiologically acceptable pKa includes a metal and a biologically active agent. The pKa of the coordination complex is less than the pKa of the biologically active agent. A pharmaceutical solution for treating a patient includes a coordination complex and water, wherein the coordination complex is at least partially soluble in the water at physiological pH and in a therapeutically efficacious concentration. A method for treating a patient includes administering a pharmaceutical solution including a coordination complex and water to a patient in need of a biologically active agent.
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