发明申请
- 专利标题: DYRK1 INHIBITORS AND USES THEREOF
- 专利标题(中): DYRK1抑制剂及其用途
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申请号: US14238925申请日: 2012-08-17
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公开(公告)号: US20140275064A1公开(公告)日: 2014-09-18
- 发明人: Bertrand Leblond , Anne-Sophie Casagrande , Laurent Desire , Alicia Foucourt , Thierry Besson
- 申请人: Bertrand Leblond , Anne-Sophie Casagrande , Laurent Desire , Alicia Foucourt , Thierry Besson
- 申请人地址: FR Paris
- 专利权人: DIAXONHIT
- 当前专利权人: DIAXONHIT
- 当前专利权人地址: FR Paris
- 优先权: EP11178190.2 20110819
- 国际申请: PCT/EP2012/066151 WO 20120817
- 主分类号: C07D513/04
- IPC分类号: C07D513/04 ; C07D277/64 ; A61K31/519 ; A61K31/5377 ; C07C219/04
摘要:
The present invention relates to novel thiazolo[5,4-f]quinazoline compounds and methods that are useful in the amelioration, treatment or control of Down's syndrome or early Alzheimer's disease or in the amelioration, treatment or control of cancers, especially solid tumors. More specifically, the invention relates to DYRK1A and/or DYRK1B inhibitors and to methods for preparing such compounds.
公开/授权文献
- US09446044B2 DYRK1 inhibitors and uses thereof 公开/授权日:2016-09-20