An applicator system for surgical fasteners includes an insertion tool having a shaft with a proximal end, a distal end, and an insertion fork connected to the distal end of the shaft, and at least one cartridge containing a plurality of surgical fasteners used for securing an implant to tissue. The surgical fasteners are removed one at a time from the cartridge by engaging one of the surgical fasteners with the insertion fork and removing the engaged surgical fastener from the cartridge. The insertion fork with the loaded surgical fastener is manually inserted through an implant and into tissue for securing the implant to the tissue.