发明申请
US20140288113A1 Extended Release Compositions Comprising Hydrocodone And Acetaminophen For Rapid Onset And Prolonged Analgesia That May Be Administered Without Regard To Food
审中-公开
包含氢可酮和对乙酰氨基酚的延长释放组合物可快速起搏和长时间的镇痛，无需食用
- 专利标题： Extended Release Compositions Comprising Hydrocodone And Acetaminophen For Rapid Onset And Prolonged Analgesia That May Be Administered Without Regard To Food
- 专利标题（中）： 包含氢可酮和对乙酰氨基酚的延长释放组合物可快速起搏和长时间的镇痛，无需食用
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申请号： US14187939申请日： 2014-02-24
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公开(公告)号： US20140288113A1公开(公告)日： 2014-09-25
- 发明人: Krishna R. Devarakonda , Michael J. Giuliani , Vishal K. Gupta , Ralph A. Heasley , Susan Shelby
- 申请人： MALLINCKRODT LLC
- 申请人地址： US MO Hazelwood
- 专利权人： MALLINCKRODT LLC
- 当前专利权人： MALLINCKRODT LLC
- 当前专利权人地址： US MO Hazelwood
- 主分类号： A61K47/08
- IPC分类号： A61K47/08 ; A61K31/485 ; A61K31/167
摘要：
The present disclosure provides an extended release pharmaceutical composition comprising hydrocodone and acetaminophen that provides a rapid onset of analgesia, and reduced levels of acetaminophen near the end of the dosing interval. Also provided are methods for reducing the risk of acetaminophen-induced hepatic damage in a subject being treated with an acetaminophen containing composition, as well as methods for treating pain in a subject in need thereof.
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