发明申请
- 专利标题： OXIDATION RESISTANT BIOPROSTHETIC TISSUES AND PREPARATION THEREOF
- 专利标题（中）： 耐氧化生物组织及其制备
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申请号： US14232005申请日： 2012-07-11
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公开(公告)号： US20140288641A1公开(公告)日： 2014-09-25
- 发明人: Robert J. Levy , Ivan Alferiev , Stanley Stachelek , Jeanne M. Connolly , Abigail Christian
- 申请人： Robert J. Levy , Ivan Alferiev , Stanley Stachelek , Jeanne M. Connolly , Abigail Christian
- 申请人地址： US PA Philadelphia
- 专利权人： The Children's Hospital of Philadelphia
- 当前专利权人： The Children's Hospital of Philadelphia
- 当前专利权人地址： US PA Philadelphia
- 国际申请： PCT/US2012/046226 WO 20120711
- 主分类号： A61F2/24
- IPC分类号： A61F2/24
摘要：
Oxidation resistant bioprosthetic tissues and oxidation resistant bioprosthetic heart valve leaflets are described. Also provided are methods for preparing the oxidation resistant bioprosthetic tissues and bioprosthetic heart valve leaflets, and methods for preventing oxidative degeneration in bioprosthetic tissues, including immobilizing covalently an effective amount of an antioxidant to the bioprosthetic tissue.
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