发明申请
US20140294832A1 MONOCLONAL ANTIBODIES AGAINST TISSUE FACTOR PATHWAY INHIBITOR (TFPI)
审中-公开
组织因子途径抑制剂（TFPI）的单克隆抗体
- 专利标题： MONOCLONAL ANTIBODIES AGAINST TISSUE FACTOR PATHWAY INHIBITOR (TFPI)
- 专利标题（中）： 组织因子途径抑制剂（TFPI）的单克隆抗体
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申请号： US14009334申请日： 2012-03-30
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公开(公告)号： US20140294832A1公开(公告)日： 2014-10-02
- 发明人: Zhuozhi Wang , John Murphy , Tobias Marquardt , Dieter Moosmayer
- 申请人： Zhuozhi Wang , John Murphy , Tobias Marquardt , Dieter Moosmayer
- 申请人地址： US NJ Whippany
- 专利权人： BAYER HEALTHCARE LLC
- 当前专利权人： BAYER HEALTHCARE LLC
- 当前专利权人地址： US NJ Whippany
- 国际申请： PCT/US12/31538 WO 20120330
- 主分类号： C07K16/38
- IPC分类号： C07K16/38
摘要：
Isolated monoclonal antibodies that bind to specific epitopes of human tissue factor pathway inhibitor (TFPI) and the isolated nucleic acid molecules encoding them are provided. Pharmaceutical compositions comprising the anti-TFPI monoclonal antibodies and methods of treating deficiencies or defects in coagulation by administration of the antibodies are also provided.
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