Programmable predication logic in command streamer instruction execution is described. In one example, the invention includes a method that includes receiving batch buffer execution start command at a command streamer, the batch buffer containing executable instructions, determining whether predication has been enabled for the instructions using the start command, if predication has been enabled, then comparing a predication condition to values stored in a predication register, and if the condition is satisfied by the predication register values, then executing the batch buffer.