发明申请
- 专利标题: COMPOSITIONS FOR THE PREPARATION OF MATURE DENDRITIC CELLS
- 专利标题(中): 用于制备成熟细胞的组合物
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申请号: US14174064申请日: 2014-02-06
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公开(公告)号: US20140302096A1公开(公告)日: 2014-10-09
- 发明人: Dolores J. SCHENDEL , Anke ZOBYWALSKI , Iris BIGALKE
- 申请人: Helmholtz Zentrum Munchen Deutsches Forschungszentrum fur Gesundheit und Umwelt (GmbH)
- 申请人地址: DE Neuherberg
- 专利权人: Helmholtz Zentrum Munchen Deutsches Forschungszentrum fur Gesundheit und Umwelt (GmbH)
- 当前专利权人: Helmholtz Zentrum Munchen Deutsches Forschungszentrum fur Gesundheit und Umwelt (GmbH)
- 当前专利权人地址: DE Neuherberg
- 优先权: EP06006373.2 20060328
- 主分类号: C12N5/0784
- IPC分类号: C12N5/0784 ; C12N15/85 ; A61K35/14 ; A61K39/00
摘要:
The invention relates to a method for in vitro maturation of at least one immate dendritic cell, comprising stimulating said immature dendritic cell with TNFα, IL-1β, IFNγ, a TLR7/8 agonist and prostaglandin E2(PG). Furthermore, the invention elates to a composition comprising these factors as well as to mature dendritic cells produced by a method of the invention.
公开/授权文献
- US09512402B2 Compositions for the preparation of mature dendritic cells 公开/授权日:2016-12-06
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