Invention Application
US20140302575A1 MICROORGANISMS AND METHODS FOR ENHANCING THE AVAILABILITY OF REDUCING EQUIVALENTS IN THE PRESENCE OF METHANOL, AND FOR PRODUCING 1,2-PROPANEDIOL, n-PROPANOL, 1,3-PROPANEDIOL, OR GLYCEROL RELATED THERETO
有权
用于提高甲醇存在下减少等效物的可行性的微生物和方法，以及生产1,2-丙二醇，正丙醇，1,3-丙二醇或与其相关的甘油的可行性
- Patent Title: MICROORGANISMS AND METHODS FOR ENHANCING THE AVAILABILITY OF REDUCING EQUIVALENTS IN THE PRESENCE OF METHANOL, AND FOR PRODUCING 1,2-PROPANEDIOL, n-PROPANOL, 1,3-PROPANEDIOL, OR GLYCEROL RELATED THERETO
- Patent Title (中): 用于提高甲醇存在下减少等效物的可行性的微生物和方法，以及生产1,2-丙二醇，正丙醇，1,3-丙二醇或与其相关的甘油的可行性
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Application No.: US14071318Application Date: 2013-11-04
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Publication No.: US20140302575A1Publication Date: 2014-10-09
- Inventor: Anthony P. Burgard , Robin E. Osterhout , Stephen J. Van Dien , Cara Ann Tracewell , Priti Pharkya , Stefan Andrae
- Applicant: Genomatica, Inc.
- Applicant Address: US CA San Diego
- Assignee: Genomatica, Inc.
- Current Assignee: Genomatica, Inc.
- Current Assignee Address: US CA San Diego
- Main IPC: C12P7/24
- IPC: C12P7/24 ; C12P7/04 ; C12P7/18 ; C12P7/20
Abstract:
Provided herein is a non-naturally occurring microbial organism having a methanol metabolic pathway that can enhance the availability of reducing equivalents in the presence of methanol. Such reducing equivalents can be used to increase the product yield of organic compounds produced by the microbial organism, such as 1,2-propanediol, n-propanol, 1,3-propanediol or glycerol. Also provided herein are methods for using such an organism to produce 1,2-propanediol, n-propanol, 1,3-propanediol or glycerol.
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