发明申请
US20140309165A1 USE OF 1,3-DIPHENYLPROP-2-EN-1-ONE DERIVATIVES FOR TREATING LIVER DISORDERS
有权
用于治疗肝脏疾病的1,3-二苯基丙-2-烯-1-酮衍生物的应用
- 专利标题: USE OF 1,3-DIPHENYLPROP-2-EN-1-ONE DERIVATIVES FOR TREATING LIVER DISORDERS
- 专利标题(中): 用于治疗肝脏疾病的1,3-二苯基丙-2-烯-1-酮衍生物的应用
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申请号: US14288482申请日: 2014-05-28
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公开(公告)号: US20140309165A1公开(公告)日: 2014-10-16
- 发明人: Raphael DARTEIL , Rémy Hanf , Dean Hum , Ingrid Dufour
- 申请人: GENFIT
- 申请人地址: FR Loos
- 专利权人: GENFIT
- 当前专利权人: GENFIT
- 当前专利权人地址: FR Loos
- 优先权: EP09306146.3 20091126
- 主分类号: A61K31/192
- IPC分类号: A61K31/192 ; A61K45/06
摘要:
The invention provides 1,3-diphenylprop-2-en-1-one derivatives and pharmaceutical compositions comprising the same for treating liver disorders, in particular those requiring the reduction of plasma level of biochemical markers such as amino-transferases. The 1,3-diphenylprop-2-en-1-one derivatives of General Formula (I) have hepatoprotective properties and can be used in methods for treating liver disorders involving the pathological disruption, inflammation, degeneration, and/or proliferation of liver cells, such as liver fibrosis or fatty liver disease.
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