发明申请
- 专利标题： PHARMACEUTICAL COMPOSITION WITH ENHANCED EFFICACY FOR INHIBITING ANGIOGENESIS
- 专利标题（中）： 具有增强抑制血管生成作用的药物组合物
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申请号： US14232598申请日： 2011-05-23
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公开(公告)号： US20140315947A1公开(公告)日： 2014-10-23
- 发明人: Ho Jeong Kwon , Gyoon Hee Han , Hye Jin Jung , Jeong Jea Seo
- 申请人： Ho Jeong Kwon , Gyoon Hee Han , Hye Jin Jung , Jeong Jea Seo
- 申请人地址： KR Seoul
- 专利权人： INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY
- 当前专利权人： INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY
- 当前专利权人地址： KR Seoul
- 优先权： KR10-2011-0023211 20110316
- 国际申请： PCT/KR2011/003773 WO 20110523
- 主分类号： C07D215/38
- IPC分类号： C07D215/38 ; C07C311/21
摘要：
The present invention relates to a pharmaceutical composition for inhibiting angiogenesis and a novel sulfonyl amide derivative compound which can be useful for the prevention or treatment of angiogenesis-related diseases or disorders. Since the compound used as an active ingredient in the pharmaceutical composition of the invention is specifically bound to UQCRB and inhibits biological functions thereof, apoptosis is not induced and angiogenic responses are inhibited. Therefore, the compound used as an active ingredient in the pharmaceutical composition of the invention can be useful as an effective and safe angiogenesis inhibitory agent.
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