Systems and methods for aggregation of multiple physical protocol data units are disclosed. In one aspect, a method of transmitting a physical layer packet to a plurality of wireless devices is disclosed. The method includes generating a physical layer packet, the packet including a plurality of payloads, wherein at least one of the payloads comprises first data addressed to a first device and second data addressed to a second device, and wherein each payload is preceded by at least a signal field in the physical layer packet, and transmitting the physical layer packet.