发明申请
- 专利标题: METHOD OF TREATING AND REDUCING THE RISK OF ACUTE MYELOGENOUS LEUKEMIA
- 专利标题(中): 治疗和减轻急性髓性白血病风险的方法
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申请号: US14232801申请日: 2012-07-13
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公开(公告)号: US20140348840A1公开(公告)日: 2014-11-27
- 发明人: Stephen D. Nimer , Lan Wang
- 申请人: Stephen D. Nimer , Lan Wang
- 申请人地址: US NY New York
- 专利权人: MEMORIAL SLOAN-KETTING CANCER CENTER
- 当前专利权人: MEMORIAL SLOAN-KETTING CANCER CENTER
- 当前专利权人地址: US NY New York
- 国际申请: PCT/US12/46721 WO 20120713
- 主分类号: G01N33/574
- IPC分类号: G01N33/574 ; C12Q1/68 ; G01N33/50
摘要:
The present invention relates to methods and compositions for treating and reducing the risk of Acute Myelogenous Leukemia (AML). In particular, the invention provides methods for identifying novel treatments for AML based on reproducible and detectable changes in AML1-ETO acetylation. The present invention further provides methods of using these treatments.