Methods for managing preparation of a medication for a patient are provided. In one aspect, a method includes receiving information indicative of an order for medication for a patient from an electronic data feed, and determining whether the order for medication for the patient can be filled with a returned medication. The method also includes providing a notification to fill the order with the returned medication when the determination indicates the order can be filled with a returned medication, and providing a notification to fill the order by preparing the medication when the determination indicates a returned medication is not available to fill the order. Systems and machine-readable media are also provided.