发明申请
- 专利标题： INHIBITORS OF HISTONE DEMETHYLASES
- 专利标题（中）： HISTONE DEMETHYLASES的抑制剂
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申请号： US14472059申请日： 2014-08-28
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公开(公告)号： US20140371195A1公开(公告)日： 2014-12-18
- 发明人: Marc Labelle , Thomas Boesen , Mukund Mehrotra , Qasim Khan , Farman Ullah
- 申请人： EpiTherapeutics ApS
- 优先权： DKPA201200599 20121002; DKPA201370112 20130227
- 主分类号： C07D213/79
- IPC分类号： C07D213/79 ; A61K31/4439 ; A61K31/444 ; C07D405/12 ; A61K31/443 ; A61K31/496 ; C07D401/12 ; A61K31/44
摘要：
The present application discloses compounds capable of modulating the activity of histone demethylases (HDMEs), which are useful for prevention and/or treatment of diseases in which genomic dysregulation is involved in the pathogenesis, such as e.g. cancer. The present application also discloses pharmaceutical compositions comprising said compounds and the use of such compounds as a medicament. The compounds take the form
公开/授权文献
- US10189787B2 Inhibitors of histone demethylases 公开/授权日：2019-01-29